A Case of Mirtazapine-Induced Pancreatitis.
Publication/Presentation Date
4-1-2023
Abstract
Acute pancreatitis is a concerning cause of hospitalization in the United States, with the most common etiologies being secondary to alcohol abuse and gallstones. Rarely, medications can trigger this inflammatory response, whether via direct toxic effects or other metabolic derangements. Mirtazapine is an antidepressant that has been associated with elevations in triglyceride levels on initiation. Relatedly, high triglyceride levels and autoimmune disorders are other causes of pancreatitis exacerbations. Here, we present the case of a female who was started on mirtazapine therapy and found to have elevated triglyceride levels. The course was complicated by acute pancreatitis requiring plasmapheresis, despite medication discontinuation, to which she responded well.
Volume
15
Issue
4
First Page
37129
Last Page
37129
ISSN
2168-8184
Published In/Presented At
Aslam, H., Ahmed, K., Iskander, P. A., Aloysius, M. M., Khurana, V., Nasr, S., & Amjad, M. A. (2023). A Case of Mirtazapine-Induced Pancreatitis. Cureus, 15(4), e37129. https://doi.org/10.7759/cureus.37129
Disciplines
Medicine and Health Sciences
PubMedID
37153315
Department(s)
Department of Medicine
Document Type
Article