Myocardial degradation and left bundle branch block predict conversion to low ejection fraction in heart failure with preserved systolic function.
Publication/Presentation Date
1-1-2008
Abstract
The authors prospectively investigated whether left bundle branch block (LBBB) and myocardial degradation as indicated by elevated troponin T (tnT) predict the phenomenon of systolic conversion to low ejection fraction (EF 40%). Thirty consecutive patients with HFPSF were included and followed over a 4-year interval. A follow-up EF assessment was performed in 25 patients. Six of 15 patients with tnT >or=0.01 ng/mL demonstrated systolic conversion to low EF on follow-up, while none of the 10 patients with tnT < 0.01 ng/mL experienced this phenomenon (P=.03). Five of the 6 converters presented with LBBB, while only 1 of the 19 nonconverters had this abnormality (P=.0007). Four of the 6 converters had an initial EF >50%. Myocardial degradation and LBBB predicted systolic conversion in HFPSF patients with nonsignificant coronary disease.
Volume
14
Issue
4
First Page
192
Last Page
196
ISSN
1527-5299
Published In/Presented At
Angheloiu, G. O., Rahaby, M., Starling, R. C., Angheloiu, V., McNamara, D. M., Yamani, M. H., & Young, J. B. (2008). Myocardial degradation and left bundle branch block predict conversion to low ejection fraction in heart failure with preserved systolic function. Congestive heart failure (Greenwich, Conn.), 14(4), 192–196. https://doi.org/10.1111/j.1751-7133.2008.07827.x
Disciplines
Medicine and Health Sciences
PubMedID
18772624
Department(s)
Department of Medicine, Cardiology Division
Document Type
Article