Factors Influencing Outcome of Prednisone Dose Reduction in Myasthenia Gravis.

Authors

M A Miano
Thomas M. Bosley MDFollow
T D Heiman-Patterson
James F. Reed III PhD, Lehigh Valley Health NetworkFollow
Robert C. Sergott MDFollow
Peter J. Savino MDFollow
N J Schatz

Publication/Presentation Date

6-1-1991

Abstract

We reviewed retrospectively 114 prednisone dose reduction attempts in 63 myasthenic patients. Dose reduction was considered successful if a patient remained asymptomatic for more than 1 year on no prednisone or a stable low dose of prednisone. Successful dose reduction attempts were more common in patients taking azathioprine, but thymectomy did not influence taper outcome. Slower rate of dose reduction and higher ending dose of prednisone improved the chance of success.

Volume

41

Issue

6

First Page

919

Last Page

921

ISSN

0028-3878

Published In/Presented At

Miano, M. A., Bosley, T. M., Heiman-Patterson, T. D., Reed, J., Sergott, R. C., Savino, P. J., & Schatz, N. J. (1991). Factors influencing outcome of prednisone dose reduction in myasthenia gravis. Neurology, 41(6), 919-921.

Disciplines

Medical Sciences | Medicine and Health Sciences

PubMedID

2046940

Department(s)

Department of Medicine, Department of Medicine Faculty, Department of Medicine Fellows and Residents

Document Type

Article