Postoperative acute disseminated encephalomyelitis after exposure to microfibrillar collagen hemostat.
Publication/Presentation Date
7-1-2008
Abstract
Microfibrillar collagen hemostat, known by its trade name Avitene, has been used in neurosurgery for decades. Complications with this product have been documented in other surgical specialties and described as mostly immune-mediated foreign-body reactions that can lead to a granulomatous reaction. There has never been a case of disseminated encephalomyelitis associated with this topical hemostatic agent. In this report the authors present a case of postoperative acute disseminated encephalomyelitis after exposure to Avitene. Possible pathophysiological mechanisms are discussed and the pertinent literature is reviewed.
Volume
109
Issue
1
First Page
149
Last Page
152
ISSN
0022-3085
Published In/Presented At
Sani, S., Boco, T., Lewis, S. L., Cochran, E., Patel, A. J., & Byrne, R. W. (2008). Postoperative acute disseminated encephalomyelitis after exposure to microfibrillar collagen hemostat. Journal of neurosurgery, 109(1), 149–152. https://doi.org/10.3171/JNS/2008/109/7/0149
Disciplines
Medicine and Health Sciences
PubMedID
18590447
Department(s)
Department of Medicine
Document Type
Article