Title

Postoperative acute disseminated encephalomyelitis after exposure to microfibrillar collagen hemostat.

Publication/Presentation Date

7-1-2008

Abstract

Microfibrillar collagen hemostat, known by its trade name Avitene, has been used in neurosurgery for decades. Complications with this product have been documented in other surgical specialties and described as mostly immune-mediated foreign-body reactions that can lead to a granulomatous reaction. There has never been a case of disseminated encephalomyelitis associated with this topical hemostatic agent. In this report the authors present a case of postoperative acute disseminated encephalomyelitis after exposure to Avitene. Possible pathophysiological mechanisms are discussed and the pertinent literature is reviewed.

Volume

109

Issue

1

First Page

149

Last Page

152

ISSN

0022-3085

Disciplines

Medicine and Health Sciences

PubMedID

18590447

Department(s)

Department of Medicine

Document Type

Article

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