Severe topiramate-associated hyperthermia resulting in persistent neurological dysfunction.
Publication/Presentation Date
1-1-2005
Abstract
Topiramate has recently been reported to cause hyperthermia as a result of oligohydrosis, primarily in pediatric patients. All cases reported to date were clinically mild, without permanent systemic or neurologic dysfunction. We report a case of severe hyperthermia and subsequent ataxia and tremor in an adult treated with topiramate. To our knowledge, this is the first case of topiramate-associated hyperthermia to result in residual cerebellar and cognitive dysfunction.
Volume
28
Issue
2
First Page
94
Last Page
95
ISSN
0362-5664
Published In/Presented At
Galicia, S. C., Lewis, S. L., & Metman, L. V. (2005). Severe topiramate-associated hyperthermia resulting in persistent neurological dysfunction. Clinical neuropharmacology, 28(2), 94–95. https://doi.org/10.1097/01.wnf.0000159957.95134.1b
Disciplines
Medicine and Health Sciences
PubMedID
15795554
Department(s)
Department of Medicine
Document Type
Article