Worldwide distribution of Waardenburg syndrome.

Publication/Presentation Date

9-1-2003

Abstract

To clarify the multiracial occurrence of Waardenburg syndrome, we present a case series and literature review. A computerized review of the English-language literature was conducted to assess the distribution of reported occurrences of Waardenburg syndrome in populations around the world. We detail the clinical features of 2 family cohorts: one of Western European origin and the other from South Asia. A computerized literature review found sporadic cases of the syndrome in many ethnic groups, including Japanese, Taiwanese, and Middle Eastern families. The highest reported incidence is among Kenyan Africans. Waardenburg syndrome accounts for between 2% and 5% of cases of congenital deafness. It was first described in Northern European cohorts and is widely identified in fair-skinned populations. We hope to raise awareness of the worldwide distribution of this important cause of hearing loss.

Volume

112

Issue

9 Pt 1

First Page

817

Last Page

820

ISSN

0003-4894

Disciplines

Medicine and Health Sciences

PubMedID

14535568

Department(s)

Department of Medicine, Department of Surgery, Department of Surgery Residents

Document Type

Article

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