Worldwide distribution of Waardenburg syndrome.
Publication/Presentation Date
9-1-2003
Abstract
To clarify the multiracial occurrence of Waardenburg syndrome, we present a case series and literature review. A computerized review of the English-language literature was conducted to assess the distribution of reported occurrences of Waardenburg syndrome in populations around the world. We detail the clinical features of 2 family cohorts: one of Western European origin and the other from South Asia. A computerized literature review found sporadic cases of the syndrome in many ethnic groups, including Japanese, Taiwanese, and Middle Eastern families. The highest reported incidence is among Kenyan Africans. Waardenburg syndrome accounts for between 2% and 5% of cases of congenital deafness. It was first described in Northern European cohorts and is widely identified in fair-skinned populations. We hope to raise awareness of the worldwide distribution of this important cause of hearing loss.
Volume
112
Issue
9 Pt 1
First Page
817
Last Page
820
ISSN
0003-4894
Published In/Presented At
Nayak, C. S., & Isaacson, G. (2003). Worldwide distribution of Waardenburg syndrome. The Annals of otology, rhinology, and laryngology, 112(9 Pt 1), 817–820. https://doi.org/10.1177/000348940311200913
Disciplines
Medicine and Health Sciences
PubMedID
14535568
Department(s)
Department of Medicine, Department of Surgery, Department of Surgery Residents
Document Type
Article