Adult-Onset Still's Disease With Extensive Lymphadenopathy Mimicking Lymphoproliferative Malignancy.

Publication/Presentation Date

7-1-2021

Abstract

Adult-onset Still's disease (AOSD), a rare systemic inflammatory disorder of unknown etiology, is considered in broad differential in patients with fever of unknown origin or unexplained lymphadenopathy. It is characterized by spiking fever, evanescent salmon-colored maculopapular rash, arthritis or arthralgia, and leukocytosis. Due to broad differentials and lack of any specific diagnostic tests, diagnosis of AOSD poses a great challenge. A concerned physician should have a high index of suspicion while dealing with patients presenting with clinical symptoms of this systemic disorder. We report a case of a 25-year-old African American female with the past medical history of AOSD, who presented with four weeks history of extensive cervical and axillary lymphadenopathy mimicking lymphoproliferative malignancy. Cases have been reported with the development of malignant lymphoma during the course of AOSD. Therefore, careful monitoring of patients with regular follow-up is vital as these patients may develop lymphoproliferative malignancy in the future.

Volume

13

Issue

7

First Page

16163

Last Page

16163

ISSN

2168-8184

Disciplines

Medicine and Health Sciences

PubMedID

34367773

Department(s)

Department of Medicine

Document Type

Article

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