Rosai-Dorfman disease with massive intracranial involvement: asymmetric response to conservative therapy.

Publication/Presentation Date

4-1-2011

Abstract

Rosai-Dorfman Disease (RDD) is a rare, idiopathic lymphoproliferative disorder. Central nervous system (CNS) involvement in this disorder is an uncommon manifestation. The clinical and radiographic appearance of CNS RDD is variable, and may mimic more common diseases. Treatment is controversial, and spontaneous remission is common. Positive outcomes have been reported with radiation therapy, or corticosteroid administration, or surgical excision. Our case is unusual in that the extracranial sites of involvement responded to corticosteroid therapy while the intracranial masses progressed.

Volume

21

Issue

2

First Page

194

Last Page

196

ISSN

1552-6569

Disciplines

Medicine and Health Sciences

PubMedID

19659569

Department(s)

Department of Medicine

Document Type

Article

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