Schwannomatosis. An unusual variant of neurofibromatosis or a distinct clinical entity?
Publication/Presentation Date
3-1-1989
Abstract
Multiple schwannomas have frequently been seen in patients with neurofibromatosis. Recently, the association of multiple cutaneous schwannomas, central nervous system tumors, and various neurologic deficits has been described in Japanese patients as a condition called schwannomatosis. We describe the first non-Japanese cases of schwannomatosis and compare and contrast this unusual condition with the well-known variants of neurofibromatosis. We conclude that the features of schwannomatosis are distinct and define a condition that does not fit into the current classification scheme of neurofibromatosis. The occurrence of multiple cutaneous schwannomas in the absence of cardinal features of neurofibromatosis may indicate the presence of central nervous system tumors or various neurologic deficits.
Volume
125
Issue
3
First Page
390
Last Page
393
ISSN
0003-987X
Published In/Presented At
Purcell, S. M., & Dixon, S. L. (1989). Schwannomatosis. An unusual variant of neurofibromatosis or a distinct clinical entity?. Archives of dermatology, 125(3), 390–393. https://doi.org/10.1001/archderm.125.3.390
Disciplines
Medicine and Health Sciences
PubMedID
2493772
Department(s)
Department of Medicine
Document Type
Article