Leptomeningeal Carcinomatosis in Epithelial Ovarian Cancer: A Diagnostic Challenge.
Publication/Presentation Date
4-12-2021
Abstract
Leptomeningeal carcinomatosis (LCM), also known as neoplastic meningitis, is a rare entity. It is generally seen in solid tumors. Ovarian cancers can infrequently cause LCM. The clinical presentation is variable. Diagnosis is made by a lumbar puncture that shows malignant cells in the cerebrospinal fluid (CSF) and usually correlates with imaging findings. Given the low individual sensitivities of lumbar puncture (55%) and magnetic resonance imaging (70%), it is recommended to combine both modalities for optimal diagnostic results. Treatment options vary depending on the type of primary carcinoma, however, the prognosis is guarded. We report a case of LCM in a patient with stage IV epithelial ovarian cancer in remission, which became a diagnostic challenge due to a lack of imaging findings.
Volume
13
Issue
4
First Page
14440
Last Page
14440
ISSN
2168-8184
Published In/Presented At
Tahir, N., Ram, A., Jain, N., Vemireddy, L. P., & Zahra, F. (2021). Leptomeningeal Carcinomatosis in Epithelial Ovarian Cancer: A Diagnostic Challenge. Cureus, 13(4), e14440. https://doi.org/10.7759/cureus.14440
Disciplines
Medicine and Health Sciences
PubMedID
33996304
Department(s)
Department of Medicine, Department of Medicine Fellows and Residents, Fellows and Residents
Document Type
Article