Abnormal Wada and neuropsychological testing results due to topiramate therapy.
Publication/Presentation Date
7-1-2000
Abstract
A 46-year-old man experienced intractable seizures since childhood. Due to lack of response to antiepilepsy drugs (AEDs), he underwent a surgical evaluation that was consistent with seizure onset in the left medial temporal lobe. While on topiramate and carbamazepine, his preoperative neuropsychological scores and sodium amytal (Wada) scores were low and may have excluded him from surgery. Repeat testing on lamotrigine and carbamazepine showed improvement in his scores, allowing him to undergo surgery. Physicians must therefore be cautious in evaluating such test scores while a patient is on topiramate.
Volume
41
Issue
7
First Page
906
Last Page
908
ISSN
0013-9580
Published In/Presented At
McCabe, P. H., & Eslinger, P. J. (2000). Abnormal Wada and neuropsychological testing results due to topiramate therapy. Epilepsia, 41(7), 906–908. https://doi.org/10.1111/j.1528-1157.2000.tb00262.x
Disciplines
Medicine and Health Sciences
PubMedID
10897166
Department(s)
Department of Medicine
Document Type
Article