Cerebral blood flow in systemic lupus erythematosus with or without cerebral complications.
Publication/Presentation Date
10-1-1987
Abstract
We measured mean cerebral blood flow (CBF) in 25 lupus patients using the xenon-133 method. The CBF was normal in lupus patients without cerebral disease and also in CNS lupus patients in remission. The CBF was lower than normal during bouts of cerebral lupus (p less than 0.001). Repeat studies showed a stereotyped pattern consisting of depressed CBF during exacerbation of CNS disease and normalization of CBF during remission (p less than 0.01). These results show that CBF is a sensitive indicator of activity of CNS disease and that the direction of change in CBF reflects the clinical course of CNS lupus.
Volume
37
Issue
10
First Page
1596
Last Page
1598
ISSN
0028-3878
Published In/Presented At
Kushner, M. J., Chawluk, J., Fazekas, F., Mandell, B., Burke, A., Jaggi, J., Rosen, M., & Reivich, M. (1987). Cerebral blood flow in systemic lupus erythematosus with or without cerebral complications. Neurology, 37(10), 1596–1598. https://doi.org/10.1212/wnl.37.10.1596
Disciplines
Medicine and Health Sciences
PubMedID
3658162
Department(s)
Department of Medicine
Document Type
Article