Title

Cerebral blood flow in systemic lupus erythematosus with or without cerebral complications.

Publication/Presentation Date

10-1-1987

Abstract

We measured mean cerebral blood flow (CBF) in 25 lupus patients using the xenon-133 method. The CBF was normal in lupus patients without cerebral disease and also in CNS lupus patients in remission. The CBF was lower than normal during bouts of cerebral lupus (p less than 0.001). Repeat studies showed a stereotyped pattern consisting of depressed CBF during exacerbation of CNS disease and normalization of CBF during remission (p less than 0.01). These results show that CBF is a sensitive indicator of activity of CNS disease and that the direction of change in CBF reflects the clinical course of CNS lupus.

Volume

37

Issue

10

First Page

1596

Last Page

1598

ISSN

0028-3878

Disciplines

Medicine and Health Sciences

PubMedID

3658162

Department(s)

Department of Medicine

Document Type

Article

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