Cerebellar glucose consumption in normal and pathologic states using fluorine-FDG and PET.
Publication/Presentation Date
11-1-1987
Abstract
We studied cerebellar metabolism in 118 subjects including young and elderly controls and patients suffering from stroke, supratentorial brain tumor and Alzheimer's disease using fluorine-18 fluorodeoxyglucose ([18F]FDG) and position emission tomography (PET). Alzheimer's disease and normal aging did not alter mean cerebellar metabolism. In stroke and tumor mean cerebellar metabolism was lower in the hemisphere contralateral to the supratentorial lesion. In tumor bilaterally significant reductions in absolute cerebellar metabolism also were noted, unlike stroke. Primary sensory stimulation did not alter absolute or relative cerebellar metabolism. These results show that absolute and relative values for cerebellar metabolism vary depending on the process under study. Thus analysis schemes employing normalization of regional metabolic data to cerebellar values may be subject to error.
Volume
28
Issue
11
First Page
1667
Last Page
1670
ISSN
0161-5505
Published In/Presented At
Kushner, M., Tobin, M., Alavi, A., Chawluk, J., Rosen, M., Fazekas, F., Alavi, J., & Reivich, M. (1987). Cerebellar glucose consumption in normal and pathologic states using fluorine-FDG and PET. Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 28(11), 1667–1670.
Disciplines
Medicine and Health Sciences
PubMedID
3499490
Department(s)
Department of Medicine
Document Type
Article