Impaired potassium and magnesium homeostasis in acute tubulo-interstitial nephritis.
Publication/Presentation Date
1-1-1985
Abstract
Although acute tubulo-interstitial nephritis is increasingly recognized as a cause of acute renal failure, little is known about renal tubular function in this disease. We report on two patients with acute tubulo-interstitial nephritis who demonstrated abnormalities in proximal and distal tubular function. The first patient developed hyperkalemia presumably from a potassium secretory defect in the distal nephron. The second patient developed an incomplete Fanconi's syndrome with glycosuria and aminoaciduria and two heretofore unreported complications of acute interstitial nephritis: hypokalemia and hypomagnesemia secondary to urinary losses of these cations. Careful monitoring of renal tubular function is indicated in patients with acute tubulo-interstitial nephritis.
Volume
41
Issue
3
First Page
273
Last Page
278
ISSN
1660-8151
Published In/Presented At
Braden GL, Germain MJ, Fitzgibbons JP. Impaired potassium and magnesium homeostasis in acute tubulo-interstitial nephritis. Nephron. 1985;41(3):273-8. doi: 10.1159/000183596. PMID: 4058627.
Disciplines
Medicine and Health Sciences
PubMedID
4058627
Department(s)
Department of Medicine
Document Type
Article