Survey for immune complexes in disseminated gonococcal arthritis-dermatitis syndrome.
Publication/Presentation Date
1-1-1979
Abstract
Seventeen patients with characteristic disseminated gonococcal arthritis-dermatitis syndrome were studied for the presence of immune complexes, and circulating gonococcal antigen and antibody. The two immune complex techniques, monoclonal rheumatoid factor assay and cryoglobulin survey, did not reveal any consistent abnormalities. Complement levels (CH50, C'3, C'4) were not consistent with peripheral consumption except in 2 patients with coinciding systemic lupus erythematosus. Gonococcal antibody was detected in 47% of patients when they presented with the syndrome. However, gonococcal antigen was not found in either serum or synovial fluid. These results do not support the hypothesis that circulating immune complexes are involved in the pathogenesis of disseminated gonococcal arthritis-dermatitis syndrome.
Volume
22
Issue
1
First Page
19
Last Page
24
ISSN
0004-3591
Published In/Presented At
Ludivico, C. L., & Myers, A. R. (1979). Survey for immune complexes in disseminated gonococcal arthritis-dermatitis syndrome. Arthritis and rheumatism, 22(1), 19–24. https://doi.org/10.1002/art.1780220104
Disciplines
Medicine and Health Sciences
PubMedID
153144
Department(s)
Department of Medicine
Document Type
Article