Monitoring cellular immune responses to cancer immunotherapy.
Publication/Presentation Date
2-1-2001
Abstract
Many clinical trials are testing the feasibility of stimulating the immune system to treat cancer. Although the efficacy of this approach will ultimately be determined by clinically relevant endpoints, detection of the magnitude and activity of the immune response is an important intermediate point in the development of these strategies. Assays that predict clinically relevant endpoints are particularly desirable for helping to determine which strategies should ultimately be tested in larger randomized clinical trials. In this review, we will discuss these cellular immunological assays and the current status of their role in clinical trials of immunotherapy.
Volume
3
Issue
1
First Page
45
Last Page
52
ISSN
1464-8431
Published In/Presented At
Morse, M. A., Clay, T. M., Hobeika, A. C., Mosca, P. J., & Lyerly, H. K. (2001). Monitoring cellular immune responses to cancer immunotherapy. Current opinion in molecular therapeutics, 3(1), 45–52.
Disciplines
Medicine and Health Sciences
PubMedID
11249731
Department(s)
Department of Medicine
Document Type
Article