Optic neuropathy and central nervous system disease secondary to Sjögren's syndrome in a child.
Publication/Presentation Date
12-1-1990
Abstract
The authors describe a 10-year-old girl in whom optic neuropathy and central nervous system (CNS) disease developed in association with primary Sjögren's syndrome. There was angiographic evidence of cerebral vasculitis and multiple infarcts present on neuroimaging. Results of parotid biopsy, cerebrospinal fluid, and serologic analyses showed abnormalities that were consistent with the diagnosis of Sjögren's syndrome. Although the patient had optic disc pallor on initial evaluation, her color vision and acuity improved with immunosuppressive therapy, as did her other neurologic symptoms. The authors believe this represents the first reported case of optic neuropathy and CNS disease associated with primary Sjögren's syndrome in the pediatric population. The possibility of improvement in visual function with early institution of immunosuppressive therapy makes prompt diagnosis essential.
Volume
97
Issue
12
First Page
1606
Last Page
1609
ISSN
0161-6420
Published In/Presented At
Berman, J. L., Kashii, S., Trachtman, M. S., & Burde, R. M. (1990). Optic neuropathy and central nervous system disease secondary to Sjögren's syndrome in a child. Ophthalmology, 97(12), 1606–1609. https://doi.org/10.1016/s0161-6420(90)32369-2
Disciplines
Medicine and Health Sciences
PubMedID
2087291
Department(s)
Department of Medicine
Document Type
Article