When do optic disc edema and peripheral neuropathy constitute poetry?

Publication/Presentation Date

1-1-1990

Abstract

A patient with chronic, bilateral optic disc edema developed multiple systemic manifestations of POEMS syndrome (polyneuropathy, organomegaly, endocrinopathy, M-protein, skin changes). A serum immunoelectrophoresis showed an abnormal serum IgG lambda protein, and urine immunoelectrophoresis revealed a monoclonal lambda protein plus an IgG lambda fragment. Bone survey and MRI scan revealed a sclerotic lesion of the first lumbar vertebra, and lymph node biopsy showed changes consistent with Castleman's disease. Thus, his optic disc edema was the presenting feature of the POEMS syndrome and osteosclerotic myeloma.

Volume

35

Issue

3

First Page

219

Last Page

225

ISSN

0039-6257

Disciplines

Medicine and Health Sciences

PubMedID

2177227

Department(s)

Department of Medicine

Document Type

Article

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