Carcinoid heart disease: current understanding and future directions.
Publication/Presentation Date
6-1-2014
Abstract
Carcinoid tumors are rare and aggressive malignancies. A multitude of vasoactive agents are central to the systemic effects of these tumors. The additional burden of cardiac dysfunction heralds a steep decline in quality of life and survival. Unfortunately, by the time carcinoid syndrome surfaces clinically, the likelihood of cardiac involvement is 50%. Although medical therapies such as somatostatin analogues may provide some symptom relief, they offer no mortality benefit. On the other hand, referral to surgery following early detection has shown increased survival. The prompt recognition of this disease is therefore of the utmost importance.
Volume
167
Issue
6
First Page
789
Last Page
795
ISSN
1097-6744
Published In/Presented At
Patel, C., Mathur, M., Escarcega, R. O., & Bove, A. A. (2014). Carcinoid heart disease: current understanding and future directions. American heart journal, 167(6), 789–795. https://doi.org/10.1016/j.ahj.2014.03.018
Disciplines
Medicine and Health Sciences
PubMedID
24890526
Department(s)
Department of Medicine
Document Type
Article