Intracranial metastases due to prostatic carcinoma.
Publication/Presentation Date
11-1-1983
Abstract
From 1973 to 1982, 189 patients were treated at the Dartmouth-Hitchcock Medical Center for Stage C or D prostatic carcinoma. In eight of these cases (4.2%), there was clinical or pathological evidence for intracranial metastases. The condition of subdural neoplastic spread, not from contiguous bone, was identified in five cases, two of which were suspected before death. Four of these five patients were thrombocytopenic or pancytopenic at the time of the diagnosis. Intraparenchymal brain metastases were identified in six cases. Cerebellar, temporal bone, cavernous sinus, and splenium infiltration by tumor were unusual findings in individual cases. The results of chest x-rays and respiratory status were poor predictors of lung metastases in four of five patients on whom autopsies were performed. This article describes the spectrum of radiographic and pathologic findings of intracranial prostatic carcinoma, and suggests that the likely mechanism of brain metastasis in these cases is by the dural veins and Virchow-Robin spaces.
Volume
52
Issue
9
First Page
1739
Last Page
1747
ISSN
0008-543X
Published In/Presented At
Castaldo, J. E., Bernat, J. L., Meier, F. A., & Schned, A. R. (1983). Intracranial metastases due to prostatic carcinoma. Cancer, 52(9), 1739–1747. https://doi.org/10.1002/1097-0142(19831101)52:9<1739::aid-cncr2820520931>3.0.co;2-c
Disciplines
Medicine and Health Sciences
PubMedID
6616423
Department(s)
Department of Medicine
Document Type
Article