Acidic fibroblast growth factor is expressed sequentially in the progression from Barrett's esophagus to esophageal adenocarcinoma.

Publication/Presentation Date

1-1-2001

Abstract

Acidic fibroblast growth factor 1 (FGF-1) is sequentially accumulated in Barrett's esophagus and its expression in glandular dysplasias is independent of esophageal adenocarcinoma. This suggests that FGF-1 immunohistochemistry could be used as an adjunct to the routine histopathologic diagnosis of dysplasia in Barrett's esophagus. The data also underscore the important role of fibroblast growth factors in tumorigenesis.

Volume

14

Issue

1

First Page

23

Last Page

27

ISSN

1120-8694

Disciplines

Medicine and Health Sciences

PubMedID

11422301

Department(s)

Department of Medicine

Document Type

Article

Share

COinS