CT evaluation of advanced seminoma treated with chemotherapy.
Publication/Presentation Date
4-1-1986
Abstract
The serial CT characteristics of nodal metastases from pure seminoma treated with chemotherapy were evaluated in 18 patients. Fifty percent of masses at presentation contained areas of low attenuation; none had calcification. After chemotherapy, masses completely resolved in four patients, partially resolved in 12 patients, and remained unchanged in one patient. The remaining patient developed progressive liver metastases during therapy and died. Pathologic evaluation of residual masses in four patients demonstrated only fibrosis. Residual masses in nine other patients demonstrated further partial resolution or remained stable over the following year; two developed calcification. These patients exhibited no clinical evidence of disease for a median follow-up of 22 or more months. Persistent but stable or resolving masses are common after chemotherapy for advanced seminoma. Unlike their nonseminomatous counterparts, they most often represent fibrosis in patients with no other clinical evidence of disease and do not warrant surgical excision.
Volume
146
Issue
4
First Page
745
Last Page
748
ISSN
0361-803X
Published In/Presented At
Stomper, P. C., Jochelson, M. S., Friedman, E. L., Garnick, M. B., & Richie, J. P. (1986). CT evaluation of advanced seminoma treated with chemotherapy. AJR. American journal of roentgenology, 146(4), 745–748. https://doi.org/10.2214/ajr.146.4.745
Disciplines
Medicine and Health Sciences
PubMedID
3485347
Department(s)
Department of Medicine
Document Type
Article