Transformation of CMML to AML presenting with acute kidney injury.
Publication/Presentation Date
8-2-2020
Abstract
Characterized by bone marrow dysplasia and peripheral blood monocytosis, chronic myelomonocytic leukemia (CMML) is one of the most aggressive chronic leukemias and has a propensity for progression to acute myeloid leukemia (AML). Patients with newly diagnosed AML generally present with symptoms related to complications of pancytopenia but can also present with renal insufficiency. We present a 79-year-old male with a past medical history of CMML and chronic kidney disease stage 3 (baseline creatinine 1.8 mg/dL) who presented with one day of inability to urinate and 20-lb unintentional weight loss, fatigue, and bone pain over 3 months. Laboratory evaluation revealed leukocytosis of 88.5 x 10
Volume
10
Issue
4
First Page
353
Last Page
357
ISSN
2000-9666
Published In/Presented At
DeBoer, R., Garrahy, I., Rettew, A., & Libera, R. (2020). Transformation of CMML to AML presenting with acute kidney injury. Journal of community hospital internal medicine perspectives, 10(4), 353–357. https://doi.org/10.1080/20009666.2020.1774271
Disciplines
Medicine and Health Sciences
PubMedID
32850097
Department(s)
Department of Medicine, Department of Medicine Fellows and Residents, Fellows and Residents
Document Type
Article