A Case of Macrophage Activation Syndrome Manifesting as the Initial Presentation of Systemic Lupus Erythematosus.
Publication/Presentation Date
6-1-2022
Abstract
Macrophage activation syndrome (MAS) is a potentially fatal complication of an autoimmune rheumatologic disease characterized by overwhelming inflammation, multiorgan failure, and high mortality if untreated. We report a rare case of a 56-year-old man who presented with fever for three weeks and had a constellation of clinical features and laboratory findings, meeting the diagnostic criteria for systemic lupus erythematosus (SLE) and SLE-associated MAS. He was treated with high dose intravenous corticosteroid and hydroxychloroquine, resulting in resolution of fever and dramatic clinical improvement.
Volume
14
Issue
6
First Page
26375
Last Page
26375
ISSN
2168-8184
Published In/Presented At
Suwal, A., Shrestha, B., Paudel, A., Paudel, R., & Basnet, S. (2022). A Case of Macrophage Activation Syndrome Manifesting as the Initial Presentation of Systemic Lupus Erythematosus. Cureus, 14(6), e26375. https://doi.org/10.7759/cureus.26375
Disciplines
Medicine and Health Sciences
PubMedID
35911271
Department(s)
Department of Medicine, Department of Medicine Fellows and Residents, Fellows and Residents
Document Type
Article