STAT1-associated intratumoural T

Authors

Katrina Au MD, Lehigh Valley Health NetworkFollow
Cécile Le Page
Runhan Ren
Liliane Meunier
Isabelle Clément
Kathrin Tyrishkin
Nichole Peterson
Jennifer Kendall-Dupont
Timothy Childs
Julie-Ann Francis
Charles H Graham
Andrew W Craig
Jeremy A Squire
Anne-Marie Mes-Masson
Madhuri Koti

Publication/Presentation Date

10-1-2016

Abstract

High-grade serous ovarian carcinoma (HGSC) accounts for 70% of all epithelial ovarian cancers but clinical management is challenged by a lack of accurate prognostic and predictive biomarkers of chemotherapy response. This study evaluated the role of Signal Transducer and Activator of Transcription 1 (STAT1) as an independent prognostic and predictive biomarker and its correlation with intratumoural CD8

Volume

2

Issue

4

First Page

259

Last Page

270

ISSN

2056-4538

Published In/Presented At

Au, K. K., Le Page, C., Ren, R., Meunier, L., Clément, I., Tyrishkin, K., Peterson, N., Kendall-Dupont, J., Childs, T., Francis, J. A., Graham, C. H., Craig, A. W., Squire, J. A., Mes-Masson, A. M., & Koti, M. (2016). STAT1-associated intratumoural TH1 immunity predicts chemotherapy resistance in high-grade serous ovarian cancer. The journal of pathology. Clinical research, 2(4), 259–270. https://doi.org/10.1002/cjp2.55

Disciplines

Medicine and Health Sciences

PubMedID

27917296

Department(s)

Department of Medicine, Section of Palliative Medicine and Hospice

Document Type

Article