Perfusion imaging in the 3-hour time window predicts a tPA-associated hemorrhage in acute ischemic stroke.
Publication/Presentation Date
2-1-2015
Abstract
Perfusion imaging is being evaluated in acute ischemic stroke patients to identify those who may benefit from reperfusion therapies beyond the standard thrombolytic time window but limited data are available on its utility in patients presenting within the standard thrombolytic time window. We report a case of a patient presenting within the 3-hour time window where computerized tomographic perfusion imaging before intravenous thrombolysis identified a large volume of severely ischemic tissue and where intravenous tissue plasminogen activator administration subsequently resulted in a fatal intracerebral hemorrhage. Whether perfusion imaging can predict an increased risk of tissue plasminogen activator-associated symptomatic hemorrhage in patients presenting within the standard thrombolytic time window requires further study.
Volume
19
Issue
3
First Page
68
Last Page
69
ISSN
2331-2637
Published In/Presented At
Rangaraju, S., Edwards, A., Dehkharghani, S., & Nahab, F. (2015). Perfusion imaging in the 3-hour time window predicts a tPA-associated hemorrhage in acute ischemic stroke. The neurologist, 19(3), 68–69. https://doi.org/10.1097/NRL.0000000000000011
Disciplines
Medicine and Health Sciences
PubMedID
25692511
Department(s)
Department of Medicine
Document Type
Article