A Case of Tuberculosis-related Leukocytoclastic Vasculitis Presenting With Peripheral Neuropathy.
Publication/Presentation Date
12-7-2018
Abstract
Tuberculous granulomatous vasculitis is commonly associated with meningitis and retinitis. We describe a 39-year-old male, with a history of pulmonary tuberculosis (TB) who presented with progressive weakness, pain, tingling and numbness in the bilateral lower extremities. Significant atrophy and weakness of the lower extremities were evident along with absent reflexes. Nerve conduction studies and electromyography showed severe axonal polyneuropathy and denervation on the lower extremities. Nerve biopsy demonstrated small vessel leukocytoclastic vasculitis without any granuloma formation. Muscle biopsy was consistent with denervation and atrophy with target fiber changes. Tuberculosis-related vasculitis causing peripheral neuropathy is extremely rare and our case is unique in manifesting this presentation.
Volume
10
Issue
12
First Page
3703
Last Page
3703
ISSN
2168-8184
Published In/Presented At
Rafiei, N., Khanlou, N., Khosa, S., Moheb, N., & Mishra, S. K. (2018). A Case of Tuberculosis-related Leukocytoclastic Vasculitis Presenting With Peripheral Neuropathy. Cureus, 10(12), e3703. https://doi.org/10.7759/cureus.3703
Disciplines
Medicine and Health Sciences
PubMedID
30788192
Department(s)
Department of Medicine
Document Type
Article