A Case of Tuberculosis-related Leukocytoclastic Vasculitis Presenting With Peripheral Neuropathy.
Tuberculous granulomatous vasculitis is commonly associated with meningitis and retinitis. We describe a 39-year-old male, with a history of pulmonary tuberculosis (TB) who presented with progressive weakness, pain, tingling and numbness in the bilateral lower extremities. Significant atrophy and weakness of the lower extremities were evident along with absent reflexes. Nerve conduction studies and electromyography showed severe axonal polyneuropathy and denervation on the lower extremities. Nerve biopsy demonstrated small vessel leukocytoclastic vasculitis without any granuloma formation. Muscle biopsy was consistent with denervation and atrophy with target fiber changes. Tuberculosis-related vasculitis causing peripheral neuropathy is extremely rare and our case is unique in manifesting this presentation.
Published In/Presented At
Rafiei, N., Khanlou, N., Khosa, S., Moheb, N., & Mishra, S. K. (2018). A Case of Tuberculosis-related Leukocytoclastic Vasculitis Presenting With Peripheral Neuropathy. Cureus, 10(12), e3703. https://doi.org/10.7759/cureus.3703
Medicine and Health Sciences
Department of Medicine