Marfan Syndrome Presenting as Spontaneous Coronary Artery Dissection and Arteriopathy.

Publication/Presentation Date

11-26-2021

Abstract

INTRODUCTION: Spontaneous coronary artery dissection (SCAD) is a term used to define a spontaneous separation of the coronary artery wall not related to underlying risk factors, such as trauma or underlying atherosclerotic disease. While SCAD has a range of different etiologies, with fibromuscular dysplasia being the most common, most cases of SCAD have no concomitant arteriopathy.

CASE REPORT: Here we describe a case of a patient who presented to our institution with SCAD and evidence of an asymptomatic arteriopathy involving extracranial segments of the carotid and vertebral arteries, later found to have a pathogenic variant in the FBN1 gene and ultimately diagnosed with Marfan syndrome. This has only been rarely described in the literature as an etiology for SCAD.

CONCLUSION: Although rare, it is important to consider underlying connective tissue disorders in patients presenting with spontaneous coronary artery dissection and arteriopathy without underlying cardiovascular risk factors.

Volume

27

Issue

1

First Page

34

Last Page

36

ISSN

2331-2637

Disciplines

Medicine and Health Sciences

PubMedID

34842564

Department(s)

Department of Medicine

Document Type

Article

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