Dexmedetomidine Reduces Incidences of Ventricular Arrhythmias in Adult Patients: A Meta-Analysis.
Publication/Presentation Date
1-1-2022
Abstract
PURPOSE: To assess the antiarrhythmic properties of dexmedetomidine in patients in the intensive care unit.
METHODS: A literature review was conducted with Ovid MEDLINE (R), Cochrane Central Register of Controlled Trials, Cochrane Database of Systematic Reviews, Embase, and Scopus.
RESULTS: We identified 6 out of 126 studies that met the selection criteria for our meta-analysis, all of which focused on the perioperative cardiac surgery period. Patients receiving dexmedetomidine demonstrated a significant reduction of the overall incidence of ventricular arrhythmias (RR 0.35, 95% CI 0.16, 0.76). In particular, dexmedetomidine significantly decreased the risk of ventricular tachycardia compared with control (RR 0.25, 95% CI 0.08, 0.80, I
CONCLUSION: From this meta-analysis, we report a decreased incidence of ventricular tachycardia with dexmedetomidine in critically ill patients. This result favors the use of dexmedetomidine for its antiarrhythmic properties.
Volume
2022
First Page
5158362
Last Page
5158362
ISSN
2090-8016
Published In/Presented At
Zhong, Q., Kumar, A., Deshmukh, A., & Bennett, C. (2022). Dexmedetomidine Reduces Incidences of Ventricular Arrhythmias in Adult Patients: A Meta-Analysis. Cardiology research and practice, 2022, 5158362. https://doi.org/10.1155/2022/5158362
Disciplines
Medicine and Health Sciences
PubMedID
35693451
Department(s)
Department of Medicine, Cardiology Division
Document Type
Article