Superoxide generation by neutrophils after exposure to a conventional peritoneal dialysis solution for different time periods.
Publication/Presentation Date
4-1-1990
Abstract
Neutrophils were isolated from canine blood and exposed to a conventional, acidic, lactate-containing peritoneal dialysis solution for 0, 2 and 4 minutes in one study and 0, 4, 7 and 10 minutes in another. Superoxide generation, expressed in nanomoles per million cells, was determined using a method based on the superoxide dismutase-inhibitable reduction of ferricytochrome c. Brief exposure of neutrophils to a conventional dialysis solution could significantly inhibit the generation of superoxide by neutrophils.
Volume
13
Issue
4
First Page
228
Last Page
230
ISSN
0391-3988
Published In/Presented At
Gupta, D. K., Ing, B. L., Manahan, F. J., Zhou, F. Q., Yu, A. W., Nawab, Z. M., & Rahman, M. A. (1990). Superoxide generation by neutrophils after exposure to a conventional peritoneal dialysis solution for different time periods. The International journal of artificial organs, 13(4), 228–230.
Disciplines
Medicine and Health Sciences
PubMedID
2165037
Department(s)
Department of Medicine
Document Type
Article