Brain Metastases With Malignant Peritoneal Mesothelioma: Never Reported Before.

Publication/Presentation Date

8-1-2023

Abstract

Malignant mesothelioma is a very rare diagnosis. Malignant mesotheliomas arise from surface linings of pleura, peritoneal cavity, or tunica vaginalis and pericardium with pleural malignant mesotheliomas being the most common. The incidence of brain metastases has been very low with malignant pleural mesotheliomas, but to date, there have not been any cases reported of brain metastasis with malignant peritoneal mesotheliomas. We present a patient diagnosed with malignant peritoneal mesothelioma and was successfully treated with immunotherapy for over two years but later presented with brain metastases. Although the patient had a surgical resection followed by brain radiation, he died three months after his diagnosis of brain metastases. Immunotherapy has revolutionized the treatment of malignant mesothelioma, and patients are living longer than before. We present this patient to increase awareness of brain metastases with malignant peritoneal mesothelioma. This case also highlights that we need to investigate different treatment options for brain metastases in patients with malignant mesothelioma as conventional treatment options like surgical resection and brain radiation are not very effective.

Volume

15

Issue

8

First Page

43744

Last Page

43744

ISSN

2168-8184

Disciplines

Medicine and Health Sciences

PubMedID

37727202

Department(s)

Department of Medicine, Hematology-Medical Oncology Division, Hematology-Medical Oncology Division Fellows and Residents, Department of Medicine Fellows and Residents, Department of Medicine Faculty, Fellows and Residents

Document Type

Article

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