Sarcoidosis manifesting as massive splenomegaly: a rare occurrence.

Publication/Presentation Date

9-1-2004

Abstract

Sarcoidosis is a multisystemic granulomatous disease of unknown origin occurring worldwide and affecting people of all races and ages. This disease manifests most frequently with bilateral hilar lymphadenopathy, pulmonary infiltrates, and skin and ocular lesions. Granulomatous inflammation of the spleen is common in patients with sarcoidosis, but splenic enlargement is unusual and massive splenomegaly quite rare. Splenomegaly is usually homogeneous, but multiple low-attenuating nodular lesions are occasionally seen and easily mistaken for lymphoma, metastases, or infections such as tuberculosis. We describe an unusual case of sarcoidosis in a woman who presented with massive splenomegaly with extensive nodularity that cleared completely with corticosteroid therapy.

Volume

328

Issue

3

First Page

170

Last Page

172

ISSN

0002-9629

Disciplines

Medicine and Health Sciences

PubMedID

15367876

Department(s)

Department of Medicine

Document Type

Article

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