The impact of severe acidemia on neurologic outcome of cardiac arrest survivors undergoing therapeutic hypothermia.
Publication/Presentation Date
12-1-2013
Abstract
INTRODUCTION: Therapeutic Hypothermia (TH) has become a standard of care in improving neurological outcomes in cardiac arrest (CA) survivors. Previous studies have defined severe acidemia as plasma pH
METHODS: A retrospective analysis was performed on 196 consecutive CA survivors (out-of-hospital CA and in-hospital CA) who underwent TH with endovascular cooling between January 2007 and October 2012. Arterial blood gas drawn prior to initiation of TH was utilized to measure pH in all patients. Shockable and non-shockable CA patients were divided into two sub-groups based on pH (pH
RESULTS: Sixty-two percent of shockable CA patients with pH≥7.20 had good neurological outcome as compared to 34% patients with pH
CONCLUSION: Presence of severe acidemia at initiation of TH in shockable CA survivors is significantly associated with poor neurological outcomes. This effect was not observed in the non-shockable CA survivors.
Volume
84
Issue
12
First Page
1723
Last Page
1727
ISSN
1873-1570
Published In/Presented At
Ganga, H. V., Kallur, K. R., Patel, N. B., Sawyer, K. N., Gowd, P. B., Nair, S. U., Puppala, V. K., Manandhi, A. R., Gupta, A. V., & Lundbye, J. B. (2013). The impact of severe acidemia on neurologic outcome of cardiac arrest survivors undergoing therapeutic hypothermia. Resuscitation, 84(12), 1723–1727. https://doi.org/10.1016/j.resuscitation.2013.07.006
Disciplines
Medicine and Health Sciences
PubMedID
23916553
Department(s)
Department of Medicine, Fellows and Residents
Document Type
Article