Coronary angioplasty with or without stent implantation for acute myocardial infarction. Stent Primary Angioplasty in Myocardial Infarction Study Group.
Publication/Presentation Date
12-23-1999
Abstract
BACKGROUND: Coronary-stent implantation is frequently performed for treatment of acute myocardial infarction. However, few studies have compared stent implantation with primary angioplasty alone.
METHODS: We designed a multicenter study to compare primary angioplasty with angioplasty accompanied by implantation of a heparin-coated Palmaz-Schatz stent. Patients with acute myocardial infarction underwent emergency catheterization and angioplasty. Those with vessels suitable for stenting were randomly assigned to undergo angioplasty with stenting (452 patients) or angioplasty alone (448 patients).
RESULTS: The mean (+/-SD) minimal luminal diameter was larger after stenting than after angioplasty alone (2.56+/-0.44 mm vs. 2.12+/-0.45 mm, P
CONCLUSIONS: In patients with acute myocardial infarction, routine implantation of a stent has clinical benefits beyond those of primary coronary angioplasty alone.
Volume
341
Issue
26
First Page
1949
Last Page
1956
ISSN
0028-4793
Published In/Presented At
Grines, C. L., Cox, D. A., Stone, G. W., Garcia, E., Mattos, L. A., Giambartolomei, A., Brodie, B. R., Madonna, O., Eijgelshoven, M., Lansky, A. J., O'Neill, W. W., & Morice, M. C. (1999). Coronary angioplasty with or without stent implantation for acute myocardial infarction. Stent Primary Angioplasty in Myocardial Infarction Study Group. The New England journal of medicine, 341(26), 1949–1956. https://doi.org/10.1056/NEJM199912233412601
Disciplines
Medicine and Health Sciences
PubMedID
10607811
Department(s)
Department of Medicine
Document Type
Article