A Multicenter comparative trial of a novel EUS-guided core biopsy needle (SharkCore
Publication/Presentation Date
1-1-2018
Abstract
BACKGROUND AND OBJECTIVES: The ability to obtain adequate tissue of solid pancreatic lesions by EUS-guided remains a challenge. The aim of this study was to compare the performance characteristics and safety of EUS-FNA for evaluating solid pancreatic lesions using the standard 22-gauge needle versus a novel EUS biopsy needle.
METHODS: This was a multicenter retrospective study of EUS-guided sampling of solid pancreatic lesions between 2009 and 2015. Patients underwent EUS-guided sampling with a 22-gauge SharkCore (SC) needle or a standard 22-gauge FNA needle. Technical success, performance characteristics of EUS-FNA, the number of needle passes required to obtain a diagnosis, diagnostic accuracy, and complications were compared.
RESULTS: A total of 1088 patients (mean age = 66 years; 49% female) with pancreatic masses underwent EUS-guided sampling with a 22-gauge SC needle (n = 115) or a standard 22-gauge FNA needle (n = 973). Technical success was 100%. The frequency of obtaining an adequate cytology by EUS-FNA was similar when using the SC and the standard needle (94.1% vs. 92.7%, respectively). The sensitivity, specificity, and diagnostic accuracy of EUS-FNA for tissue diagnosis were not significantly different between two needles. Adequate sample collection leading to a definite diagnosis was achieved by the 1
CONCLUSIONS: The EUS SC biopsy needle is safe and technically feasible for EUS-FNA of solid pancreatic mass lesions. Preliminary results suggest that the SC needle has a diagnostic yield similar to the standard EUS needle and significantly reduces the number of needle passes required to obtain a tissue diagnosis.
Volume
7
Issue
1
First Page
34
Last Page
40
ISSN
2303-9027
Published In/Presented At
Naveed, M., Siddiqui, A. A., Kowalski, T. E., Loren, D. E., Khalid, A., Soomro, A., Mazhar, S. M., Yoo, J., Hasan, R., Yalamanchili, S., Tarangelo, N., Taylor, L. J., & Adler, D. G. (2018). A Multicenter comparative trial of a novel EUS-guided core biopsy needle (SharkCore™) with the 22-gauge needle in patients with solid pancreatic mass lesions. Endoscopic ultrasound, 7(1), 34–40. https://doi.org/10.4103/eus.eus_27_17
Disciplines
Medicine and Health Sciences
PubMedID
29451167
Department(s)
Department of Medicine
Document Type
Article