Trends in the hospitalization of ischemic stroke in the United States, 1998-2007.

Publication/Presentation Date

4-1-2012

Abstract

BACKGROUND: The late 1990s/early 2000s was a time of change in both the prevention and acute care of ischemic stroke, with primary prevention driven by increased utilization of antihypertensive, antiplatelet, anticoagulation, and lipid-lowering agents.

AIM: To examine whether ischemic stroke hospitalization rates and outcomes in the United States have changed.

METHOD: We retrospectively identified 894 169 hospitalizations with a primary diagnosis of ischemic stroke from 1 January 1998 through to 31 December 2007 in the Nationwide Inpatient Sample, the largest all-payer healthcare database in the United States. Annual, national case estimates were combined with US Census data to derive age-adjusted and age-specific population hospitalization rates. Temporal trends were tested using linear regression.

RESULTS: From 1998 through 2007, there were an estimated 4 382 336 ischemic stroke hospitalizations in the United States. Overall, the age-adjusted rate of ischemic stroke hospitalization decreased from 184 to 128 per 100 000 (P < 0·0001). Age-specific rates decreased among those 55+ years old (P < 0·0001), but increased among those 25-34 and 35-44 years old (P < 0·001 and P < 0·0001, respectively). Rates among those

CONCLUSION: In 1998 through to 2007, the overall rate of ischemic stroke hospitalization in the United States decreased. However, rates among young adults increased. In-hospital mortality rates decreased over the study period.

Volume

7

Issue

3

First Page

195

Last Page

201

ISSN

1747-4949

Disciplines

Medicine and Health Sciences

PubMedID

22151527

Department(s)

Department of Medicine

Document Type

Article

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