Analysis of the responses of frog motoneurons to epinephrine and norepinephrine.
Publication/Presentation Date
8-29-1986
Abstract
Epinephrine and norepinephrine were applied to the isolated superfused frog spinal cord hyperpolarized motoneurons. The hyperpolarization was related to both direct and indirect actions and the indirect effects were produced by activation of alpha 2-adrenoceptors. In about half of the spinal cords a slow depolarization caused by activation of beta-receptors was seen and was largely attributable to direct actions of the catecholamines on motoneuron membranes. In a small number of preparations an early alpha 1-mediated depolarization was noted. The results suggest that catecholamines released from terminals in the frog ventral horn could exert a modulatory action on the motoneuron output from the spinal cord.
Volume
69
Issue
2
First Page
150
Last Page
155
ISSN
0304-3940
Published In/Presented At
Wohlberg, C. J., Davidoff, R. A., & Hackman, J. C. (1986). Analysis of the responses of frog motoneurons to epinephrine and norepinephrine. Neuroscience letters, 69(2), 150–155. https://doi.org/10.1016/0304-3940(86)90594-x
Disciplines
Medicine and Health Sciences
PubMedID
3763041
Department(s)
Department of Medicine
Document Type
Article