Prognostic Performance of the IABP-SHOCK II Risk Score Among Cardiogenic Shock Subtypes in the Critical Care Cardiology Trials Network Registry.
Publication/Presentation Date
1-6-2024
Abstract
BACKGROUND: Risk stratification has potential to guide triage and decision-making in cardiogenic shock (CS). We assessed the prognostic performance of the IABP-SHOCK II score, derived in Europe for acute myocardial infarct-related CS (AMI-CS), in a contemporary North American cohort, including different CS phenotypes.
METHODS: The Critical Care Cardiology Trials Network (CCCTN) coordinated by the TIMI Study Group is a multicenter network of cardiac intensive care units (CICU). Participating centers annually contribute ≥2 months of consecutive medical CICU admissions. The IABP-SHOCK II risk score includes age >73 years, prior stroke, admission glucose >191 mg/dl, creatinine >1.5 mg/dl, lactate >5 mmol/l, and post-PCI TIMI flow grade
RESULTS: Of 17,852 medical CICU admissions 5,340 patients across 35 sites were admitted with CS. In patients with AMI-CS (n=912), the IABP-SHOCK II score predicted a >3-fold gradient in in-hospital mortality (low risk = 26.5%, intermediate risk =52.2%, high risk = 77.5%, p
CONCLUSIONS: In an unselected international multicenter registry of patients admitted with CS, the IABP- SHOCK II score only moderately predicted in-hospital mortality in a broad population of CS regardless of etiology or irrespective of right, left, or bi-ventricular involvement.
ISSN
1097-6744
Published In/Presented At
Alviar, C. L., Li, B. K., Keller, N. M., Bohula-May, E., Barnett, C., Berg, D. D., Burke, J. A., Chaudhry, S. P., Daniels, L. B., DeFilippis, A. P., Gerber, D., Horowitz, J., Jentzer, J. C., Katrapati, P., Keeley, E., Lawler, P. R., Park, J. G., Sinha, S. S., Snell, J., Solomon, M. A., … CCCTN Investigators (2024). Prognostic Performance of the IABP-SHOCK II Risk Score Among Cardiogenic Shock Subtypes in the Critical Care Cardiology Trials Network Registry. American heart journal, S0002-8703(23)00361-7. Advance online publication. https://doi.org/10.1016/j.ahj.2023.12.018
Disciplines
Medicine and Health Sciences
PubMedID
38190931
Department(s)
Department of Medicine, Cardiology Division
Document Type
Article