A multicenter study of Pneumocystis choroidopathy.
Publication/Presentation Date
7-15-1991
Abstract
We studied 21 patients with the acquired immunodeficiency syndrome and presumed Pneumocystic carinii choroidopathy. The lesions were characteristically yellow to pale yellow in color, appeared at the level of the choroid, and were found in the posterior pole. They varied in size from 300 to 3,000 microns, initially increasing in number before treatment and eventually resolving after systemic antimicrobial therapy. Of the 21 patients, 18 (86%) had received inhaled pentamidine as prophylaxis against Pneumocystis pneumonia. Visual acuity and visual field testing showed little evidence of retinal destruction. Survival after the diagnosis of the choroidopathy ranged from two to 36 weeks. Pneumocystic choroidopathy offers an easily accessible clue to disseminated Pneumocystis infection. When comparing drugs for Pneumocystis prophylaxis, careful ocular examination can provide one indicator of the relative efficacy of protection against extrapulmonary disease.
Volume
112
Issue
1
First Page
15
Last Page
22
ISSN
0002-9394
Published In/Presented At
Shami, M. J., Freeman, W., Friedberg, D., Siderides, E., Listhaus, A., & Ai, E. (1991). A multicenter study of Pneumocystis choroidopathy. American journal of ophthalmology, 112(1), 15–22. https://doi.org/10.1016/s0002-9394(14)76206-3
Disciplines
Medicine and Health Sciences
PubMedID
1882916
Department(s)
Department of Medicine
Document Type
Article