Cardiac magnetic resonance imaging of eosinophilic endomyocardial disease.
Publication/Presentation Date
6-6-2008
Abstract
Idiopathic hypereosinophilic syndrome (HES) is rare and frequently involves the heart with development of endomyocardial fibrosis, a characteristic restrictive cardiomyopathy. Non-invasive diagnosis is frequently challenging. Recent developments in cardiac magnetic resonance (CMR) imaging techniques offer potential for improved detection and characterization of this entity. We describe the use of contrast-enhanced CMR to demonstrate thrombus, endomyocardial fibrosis and inflammation in eosinophilic endomyocardial disease. A three-layered appearance consisting of normal myocardium, thickened fibrotic endocardium with inflammatory exudate, and overlying thrombus was seen on cine-images. Post-contrast perfusion and delayed enhancement images confirmed the presence and location of endomyocardial fibrosis and thrombus. CMR is an important and powerful addition to current non-invasive diagnostic tools for the clinical diagnosis of eosinophilic endomyocardial disease, and may potentially obviate the need for cardiac biopsy in the future.
Volume
126
Issue
3
First Page
50
Last Page
52
ISSN
1874-1754
Published In/Presented At
Syed, I. S., Martinez, M. W., Feng, D. L., & Glockner, J. F. (2008). Cardiac magnetic resonance imaging of eosinophilic endomyocardial disease. International journal of cardiology, 126(3), e50–e52. https://doi.org/10.1016/j.ijcard.2007.01.019
Disciplines
Medicine and Health Sciences
PubMedID
17399811
Department(s)
Department of Medicine
Document Type
Article