Attenuation of HIV-1 infection by other microbial agents.
Publication/Presentation Date
9-15-2005
Abstract
Although potentiation of human immunodeficiency virus (HIV) type 1 (HIV-1) infection has been known to occur in coinfection with a variety of pathogens and types of vaccination, there are emerging data on specific infectious agents that may attenuate HIV-1 infection. New literature suggests that certain pathogens are capable of inhibiting HIV-1 replication. These include GB virus C, measles virus, Orientia tsutsugamushi, and human T lymphotropic virus types 1 and 2. In addition, there are conflicting data on the effects of Mycobacterium tuberculosis on the replication of HIV-1, with some suggesting that this organism may inhibit HIV-1 replication. Also remaining controversial are the possible protective effects of HIV type 2 against HIV-1 infection. In this review, we summarize and critically discuss the body of emerging literature concerning infections that may have the ability to attenuate HIV-1 infection.
Volume
192
Issue
6
First Page
1003
Last Page
1009
ISSN
0022-1899
Published In/Presented At
Kannangara, S., DeSimone, J. A., & Pomerantz, R. J. (2005). Attenuation of HIV-1 infection by other microbial agents. The Journal of infectious diseases, 192(6), 1003–1009. https://doi.org/10.1086/432767
Disciplines
Medicine and Health Sciences
PubMedID
16107952
Department(s)
Department of Medicine
Document Type
Article