Etanercept for the treatment of psoriasis in the elderly.
Publication/Presentation Date
9-1-2006
Abstract
This study's objective was to analyze the effect of etanercept on Psoriasis Area and Severity Index (PASI) 50, PASI 75, and Dermatology Life Quality Index in geriatric and nongeriatric populations. We conducted a post hoc analysis of two large phase III randomized placebo trials of etanercept. There were no statistically significant differences between the elderly and young with regard to the number of patients reaching a PASI 50 or PASI 75 at any of the 3 dosing regimens. Baseline Dermatology Life Quality Index scores were not statistically significant between both groups and both the elderly and young had similar changes in Dermatology Life Quality Index with therapy. A limitation of the study was the small number of patients in the elderly group. In conclusion, psoriasis and its treatment has a similar impact on quality of life in the elderly as it does in the young.
Volume
55
Issue
3
First Page
517
Last Page
519
ISSN
1097-6787
Published In/Presented At
Militello, G., Xia, A., Stevens, S. R., & Van Voorhees, A. S. (2006). Etanercept for the treatment of psoriasis in the elderly. Journal of the American Academy of Dermatology, 55(3), 517–519. https://doi.org/10.1016/j.jaad.2006.02.010
Disciplines
Medicine and Health Sciences
PubMedID
16908365
Department(s)
Department of Medicine
Document Type
Article