Hypersplenism induced by splenic vein ligation.

Publication/Presentation Date

3-1-2008

Abstract

Warm autoimmune hemolytic anemia (AIHA) is a rare clinical entity. It is usually caused by an IgG autoantibody directed against the red blood cell membrane that causes extravascular hemolysis predominantly in the spleen. As a result, disease states or procedures that result in hypersplenism would be expected to increase red cell destruction in patients with an underlying warm AIHA. We present the case of a patient with a previously undiagnosed warm AIHA, who developed worsening hemolysis after undergoing splenic vein ligation during a pancreaticoduodenectomy to remove a neuroendocrine tumor.

Volume

83

Issue

3

First Page

242

Last Page

244

ISSN

0361-8609

Disciplines

Medicine and Health Sciences

PubMedID

17874452

Department(s)

Department of Medicine

Document Type

Article

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