Lipoproteins in heart disease.
Publication/Presentation Date
7-1-1996
Abstract
Most lipids are carried in the circulation by lipoproteins. Lipoproteins and their associated proteins, called apolipoproteins, are currently being studied in an effort to further our understanding of atherosclerotic cardiovascular disease. Lipoprotein assembly, secretion, transportation, modification and clearance are essential elements of healthy lipid metabolism. When one or more of these key steps becomes altered, various disease states are induced. Current data suggest that lipoprotein(a), a low density lipoprotein (LDL)-like particle, is an acute phase reactant that plays a critical role in the modulation of fibrinolysis. Several aspects of lipoproteins and lipoprotein metabolism will be examined. Emphasis will be placed on the proatherogenic and thrombogenic effects of oxidized LDL.
Volume
11
Issue
4
First Page
338
Last Page
345
ISSN
0267-6591
Published In/Presented At
Basile-Borgia, A., & Abel, J. H. (1996). Lipoproteins in heart disease. Perfusion, 11(4), 338–345. https://doi.org/10.1177/026765919601100407
Disciplines
Medicine and Health Sciences
PubMedID
8884863
Department(s)
Department of Medicine
Document Type
Article