Glycosphingolipid hydrolases: properties and molecular genetics.
Publication/Presentation Date
10-7-1977
Abstract
This is a review of the properties and molecular genetics of six lysosomal hydrolases: beta-galactosidase, hexosaminidases A and B, alpha-galactosidase, beta-glucosidase and alpha-fucosidase. Each enzyme is discussed with regards to isoenzymes and substrate specificity, subunit structure, genetic relationship of isoenzymes and genetic variants. The molecular genetics of human diseases caused by deficiencies of each enzyme are discussed.
Volume
17
Issue
3
First Page
125
Last Page
140
ISSN
0300-8177
Published In/Presented At
Wan Ho, M., Norden, A. G., Alhadeff, J. A., & O'Brien, J. S. (1977). Glycosphingolipid hydrolases: properties and molecular genetics. Molecular and cellular biochemistry, 17(3), 125–140. https://doi.org/10.1007/BF01730832
Disciplines
Medicine and Health Sciences
PubMedID
200837
Department(s)
Department of Medicine
Document Type
Article