Ivabradine and Milrinone-Bridge to Recovery in New HFrEF With Low-Output Heart Failure.
Publication/Presentation Date
9-1-2024
Abstract
In patients with newly diagnosed heart failure with reduced ejection fraction (HFrEF) who are on a downward clinical trajectory, options are mostly limited to left ventricular assist device and transplantation. However, in those with factors favorable for reverse remodeling, every effort should be made to promote native myocardial recovery. We present three patients with newly diagnosed severe HFrEF, NYHA Class 3-4 symptoms, and low cardiac output with and without organ malperfusion. Ivabradine and/or home milrinone were used during their tenuous hemodynamic period as a bridge to optimize guideline-directed medical therapy (GDMT), device therapy, and eventual reverse remodeling. Evidence of structural heart improvement continued far beyond 1 year.
Volume
2024
First Page
5278240
Last Page
5278240
ISSN
2090-6404
Published In/Presented At
Racharla, L., Gitzel, L., Joseph, M., Guthier, D., & Hawwa, N. (2024). Ivabradine and Milrinone-Bridge to Recovery in New HFrEF With Low-Output Heart Failure. Case reports in cardiology, 2024, 5278240. https://doi.org/10.1155/2024/5278240
Disciplines
Medicine and Health Sciences
PubMedID
39257453
Department(s)
Department of Medicine, Cardiology Division, Fellows and Residents, USF-LVHN SELECT Program, USF-LVHN SELECT Program Students
Document Type
Article