Mydriatic solution for outpatient indirect ophthalmoscopy.
Publication/Presentation Date
9-1-1980
Abstract
A mydriatic used for outpatient indirect ophthalmoscopy should produce prompt, maximal, transient mydrasis after a single instillation. Cycloplegia or systemic side effects should be minimal. A solution of tropicamide with phenylephrine hydrochloride seems to achieve this most effectively. In a general retina clinic population, the percentage of pupils dilated, the degree of dilation, and the resistence of the dilation to intense illumination were used to evaluate various concentrations of the drugs. Eight-tenths percent tropicamide with 5% phenylephrine adequately dilated 98.8% of the eyes, among which 25% had dark irides and 9% were receiving miotic therapy. Reduction of the concentration of either component produced less adequate mydriasis; an increase of the tropicamide concentration resulted in a saturated solution with drug precipitate forming on storage and a less adequate dilation. With the optimal combination, 1 drop adequately dilates the general population; 2 drops appear on more effective than 1.
Volume
98
Issue
9
First Page
1572
Last Page
1574
ISSN
0003-9950
Published In/Presented At
Sinclair, S. H., Pelham, V., Giovanoni, R., & Regan, C. D. (1980). Mydriatic solution for outpatient indirect ophthalmoscopy. Archives of ophthalmology (Chicago, Ill. : 1960), 98(9), 1572–1574. https://doi.org/10.1001/archopht.1980.01020040424004
Disciplines
Medicine and Health Sciences
PubMedID
7425917
Department(s)
Department of Medicine
Document Type
Article